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VALPROIC ACID
Descriptors Found:
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DeCS
Descriptor
English
:
Valproic Acid
Descriptor
Spanish
:
Ácido Valproico
Descriptor
Portuguese
:
Ácido Valpróico
Synonyms
English
:
Dipropyl Acetate
Divalproex
Sodium Valproate
Tree Number:
D02.241.081.944.509.900
D10.251.400.895.593.900
Definition
English
:
A fatty acid with anticonvulsant properties used in the treatment of
epilepsy
. The mechanisms of its therapeutic actions are not well understood. It may act by increasing
GAMMA-AMINOBUTYRIC ACID
levels in the
brain
or by altering the properties of voltage dependent
sodium channels.
Pharmacological Action:
Anticonvulsants
Antimanic Agents
Enzyme Inhibitors
GABA Agents
History Note
English
:
91; was VALPROATE 1979-90; was DIPROPYL ACETATE see under VALERATES 1975-78
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
29291
Unique Identifier:
D014635
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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